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Search results for "Sickle cell disease"

Results of a preliminary study by investigators at St Jude Children’s Research Hospital, showed treating babies who have sickle cell anemia ( SCA ) with oral liquid Hydroxyurea appears to prevent the ...


Blood Products Advisory Committee ( BPAC ) of the FDA ( Food and Drug Administration ) has given a positive review of Exjade ( Deferasirox ). Exjade is once-daily oral iron chelator for the trea ...


Researchers at the Medical College of Georgia have found that nitric oxide may help normalize a sickle cell patient’s hemoglobin by restoring the natural charge and shape to the oxygen-carrying compon ...


No consensus exists on whether preoperative blood transfusions are beneficial in patients with sickle-cell disease. A study has assessed whether perioperative complication rates would be altered by pr ...


In sickle cell disease ( SCD ), pain is considered chronic if it lasts more than 3 months. People with sickle cell disease experience both nociceptive and neuropathic pain. Nociceptive pain is a hallm ...


Avascular necrosis ( AVN, also known as aseptic necrosis, osteonecrosis, or ischemic necrosis ) is bone death due to compromised blood supply. Necrosis can occur when capillaries are occluded by sic ...


Leg ulcers are a common complication of sickle cell disease ( SCD ) in general and sickle-cell anaemia ( SCA ) in particular. Leg ulceration was reported in all of the first four people with sickle ce ...


Pulmonary hypertension ( PH ) is defined as an elevation of the resting mean pulmonary arterial pressure ( greater than or equal to 25 mmHg ) as determined by right heart catheterization ( RHC ). Th ...


Chronic kidney disease ( CKD ) is defined as either having a glomerular filtration rate ( GFR ) of less than 60 mL/min/1.73 mL for more than 3 months with or without kidney damage or having evidence o ...


Chronic ophthalmological complications of SCD include proliferative sickle retinopathy ( PSR ) and vitreous hemorrhage. They occur in up to 50% of individuals with SCD, and are found more frequently ...


Vitamin D is increasingly recognized for its roles in non-skeletal disorders. Patients with sickle cell disease ( SCD ) have a high prevalence of vitamin D deficiency but data are limited with respect ...