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Initial clinical results from Pivotal Phase III Special Protocol Assessment ( SPA ) trials using Revlimid ( Lenalidomide ) as a new approach in the treatment of heavily pretreated patients with relaps ...


Two phase II studies with Bortezomib ( Velcade ) showed very high response rates in front-line multiple myeloma. Overall response rates ranged from 88 to 95 percent with complete and near complete r ...


Researchers, led by scientists at Rockefeller University, found a gene mutation not previously known to be related to Fanconi anemia, and they say that BRIP1 is the first gene associated with the dise ...


The results from the phase III APEX study have been published in The New England Journal of Medicine. The study showed Velcade ( Bortezomib ) was superior in survival, time to disease progression, an ...


Results of a preliminary study by investigators at St Jude Children’s Research Hospital, showed treating babies who have sickle cell anemia ( SCA ) with oral liquid Hydroxyurea appears to prevent the ...


Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, iron-containing molecule that is a component of hemoglobin and myoglobin. The research sugg ...


Researchers at the Virginia Commonwealth University ( VCU ) studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have show ...


Blood Products Advisory Committee ( BPAC ) of the FDA ( Food and Drug Administration ) has given a positive review of Exjade ( Deferasirox ). Exjade is once-daily oral iron chelator for the trea ...


A study has demonstrated that elderly people with the lowest and highest hemoglobin concentrations are at increased risk of death. Increasing evidence indicates that anemia is common in the elderly ...


Interim results from an open-label study have shown that long-term administration ( up to 48 weeks ) of its investigational therapy AMG 531 was generally well-tolerated and stimulated platelet product ...


Interim data from a Phase 2 study evaluating the use of 500 mcg of Aranesp ( Darbepoetin alfa ) administered every three weeks to treat anemia in patients with a bone marrow disorder known as myelodys ...


A drug used to treat kidney cancer also targets a genetic mutation active in about one third of patients with acute myeloid leukemia ( AML ), the most common and lethal form of adult leukemia, researc ...


A subset analysis of the international phase III trial ( AZA-001 ) has demonstrated that the overall survival benefit observed in higher-risk myelodysplastic syndromes ( MDS ) patients extended to pat ...


Four studies that highlight significant advances in treatment and survival outcomes for patients with various forms of thrombocytopenia, a group of bleeding disorders characterized by a low number of ...


Novel treatments have shown improvements in survival and response rates for leukemia and lymphoma. The use of Dexamethasone early in the treatment of children with acute lymphoblastic leukemia, the ...